First breakthrough case delivering targeted therapy for pancreatic lesions in USA
Creo Medical accelerates US clinical adoption and commercial rollout of MicroBlate Fine
Creo Medical Group plc (AIM: CREO), the medical device company specialising in advanced energy solutions for therapeutic endoscopy, announces a clinical and commercial update on MicroBlate Fine, its precision microwave ablation platform, as momentum builds across early US clinical adoption and commercial rollout.
MicroBlate Fine has now crossed the threshold of 50 clinical cases worldwide across multiple institutions, with particularly strong engagement from leading US interventional endoscopy centres. MicroBlate Fine is being further evaluated through an international investigator‑led study across the US, Europe and Asia‑Pacific, with Banner Health in the US acting as the principal investigative site. The study is targeting patients with pancreatic and liver lesions. The first patient was treated in March 2026.
In the US, MicroBlate Fine has recently been used to perform the first endoscopic ultrasound (“EUS”) guided microwave ablation of a pancreatic lesion, highlighting its applicability in complex and previously difficult‑to‑treat anatomy. MicroBlate Fine enables EUS‑guided microwave ablation through a flexible 19G needle, providing precise, controlled and homogeneous energy delivery while integrating seamlessly into existing EUS workflows. The device is powered by Creo’s CROMA™ Advanced Energy Platform.
Early adoption by US centres of excellence plays a critical role in accelerating broader market acceptance and supports future commercial scale‑up in what represents one of the world’s largest therapeutic endoscopy markets. MicroBlate Fine provides a strategic entry point into high‑value microwave ablation procedures, with the potential to enhance recurring revenues and increase utilisation of Creo’s broader advanced energy ecosystem, particularly in the US market.
The Company expects continued expansion of site adoption through 2026, alongside growing US clinical engagement, supporting both near‑term revenue generation and longer‑term market penetration in advanced therapeutic endoscopy.
Dr Shailendra Singh, Director of Advanced Endoscopy and Associate Professor at West Virginia University, said:
“The ability to deliver microwave ablation under EUS guidance offers precise, controlled and homogeneous energy delivery, enabling targeted therapy for pancreatic lesions. Technologies such as this expand the reach of interventional EUS and have the potential to significantly broaden treatment options for patients.”
Craig Gulliford, Chief Executive Officer of Creo Medical, said:
“Early US clinical engagement with MicroBlate Fine, combined with progressing international studies and encouraging commercial traction, reinforces our belief that this product can become an important growth driver for the Group. With attractive per‑procedure economics and clear portfolio pull‑through, MicroBlate Fine strengthens our position in therapeutic endoscopy and enhances our commercial opportunity.
“As always, patient benefits come first and the fact that previously very sick patients are being put back on to routine follow-up with no evidence of disease at their first follow-up consultation is extremely rewarding for the whole Creo Team.”
Posted 07/05/2026
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