Media Centre Careers Investors Contact Us

Designed for complexity.
Ready to adapt.

Advanced therapeutic procedures demand control across variable anatomy, tissue states and clinical objectives.

SpydrBlade Flex combines controlled bipolar RF resection with on-demand super-high-frequency microwave coagulation in a single rotatable therapeutic instrument, bringing Creo’s Adaptive Multimodal Energy approach to advanced flexible endoscopy.

Controlled tissue division using advanced bipolar RF energy, with the jaws open, closed or through the tip
On-demand microwave coagulation to support haemostasis when required
Adaptable access and orientation through a fully rotatable design
Controlled depth of penetration supported by the purpose-designed jaw architecture

Request a trial Download brochure

Adaptive Multimodal Energy in action

Powered by the CROMA Platform and Kamaptive™ Technology, Creo’s proprietary expression of Adaptive Multimodal Energy, SpydrBlade Flex brings together two complementary energy modalities within one flexible therapeutic instrument.

Advanced bipolar RF energy supports controlled tissue resection, while super-high-frequency microwave energy provides on-demand coagulation. Each modality is designed around a distinct clinical objective, giving clinicians adaptable therapeutic capability through one shared energy platform.

From fibrotic dissection to controlled myotomy

SpydrBlade Flex is designed to support different forms of tissue interaction across a growing range of advanced endoscopic applications - from colorectal resection and fibrotic dissection to septotomy and myotomy.

Grasp. Control. Divide | Colorectal ESD

A scissor-type advanced-energy approach to controlled colonic polyp resection. Watch Dr Roser Vega perform an advanced Colorectal ESD with SpydrBlade Flex at London Live Endoscopy 2025.

Precise Tissue Division | Z-POEM

This 5-minute educational video, published in VideoGIE, demonstrates how SpydrBlade Flex enables precise tissue division, maintains a clear operative field, and supports a fast, safe, and controlled septotomy.

One therapeutic instrument. Multiple cutting approaches.

Glide Cut

Snip Cut

Tip Cut

Discover how SpydrBlade Flex adapts across ESD, Zenker's diverticulum, POEM and more.

Explore clinical evidence

SpydrBlade Flex - Device Overview

How SpydrBlade Flex works

Further information

Case Studies

View our case studies for more examples of SpydrBlade Flex cases.

View case studies

Join our Community

Join our community for exclusive access to educational content on SpydrBlade Flex in action.

Join community

SpydrBlade Flex

View the dedicated product page for more information on SpydrBlade Flex.

View product page

References:

1: Data on file

2: Randomized controlled trial comparing the clinical efficacy of a bipolar radiofrequency cutting knife versus monopolar cutting knife during esophageal POEM: A multicenter non-inferiority study. Salmaan Jawaid, Mohan Ramchandani, Eduardo Albéniz, Pradev Inavolu, Zaheer Nabi, Mai Khalaf, Tara Keihanian, Mohamed Othman. AB732 Gastrointestinal Endoscopy Volume 99, No. 6S : 2024

Speak to your local team about SpydrBlade Flex

Request a trial

This information contained in this website is intended as general information to demonstrate Creo Medical’s product range for healthcare professionals only and not the general public. Not all products are cleared/approved for use in all territories, and accordingly the availability of products may vary depending on the territory and current regulatory requirements and/or medical practices in such territory. Please read our full disclaimer for further details.

Designed for complexity.
Ready to adapt.

Adaptive Multimodal Energy in action

Watch Dr Carsten Triller's case study - Rectal Broad-Based Polyp Suspected of Cancer Using SpydrBlade Flex

On-demand coagulation when the procedure requires it. Controlled SHF microwave coagulation provides a complementary tissue effect to support vessel management and haemostasis during advanced therapeutic procedures.